Logitech Signature M650 review

The Signature M650 is the everyday office mouse we would hand to most people who do not need extra buttons. Its main trick is size choice: Logitech recommends the standard M650 for small to medium hands, the M650 L for large hands, and the M650 L Left for left-handed users, all at $39.99. The shape is contoured with rubber side grips and a soft thumb area. Logitech's SmartWheel switches automatically from precise line-by-line scrolling to fast scrolling when you flick it. It connects over Bluetooth Low Energy or a Logi Bolt receiver with a 33 ft range and runs on one AA battery that Logitech rates at up to 24 months on the receiver and 20 months on Bluetooth. It is certified Works With Chromebook and supports Windows, macOS, Linux, iPadOS and Android. You give up a thumb wheel, programmable extras beyond five buttons, and glass tracking.

Who it is for

Office workers who want a comfortable mouse under $40

Price

$39.99 at Logitech's US store when checked.

$39.99 Size Signature M650
Quoted from the vendor pricing page on November 12, 2026.

Key features

• SmartWheel that switches between line-by-line and fast scrolling
• Three versions: M650 for small to medium hands, M650 L for large hands, M650 L Left for left-handed users
• Rubber side grips and a soft thumb area
• Bluetooth Low Energy or Logi Bolt USB receiver, 33 ft (10 m) range
• One AA battery rated for up to 24 months with the receiver, 20 months on Bluetooth

Strengths and weaknesses

• Strength: Size options for small, large and left hands at one price
• Strength: Works with Windows, macOS, Linux, iPadOS, Android and is Works With Chromebook certified
• Strength: No recharging for up to 2 years on the receiver
• Weakness: 5 buttons and no thumb wheel
• Weakness: Sensor tops out at 4,000 DPI
• Weakness: No glass tracking claimed

Key facts

• Weight: 101.4 g (M650), 115.4 g (M650 L)
• Sensor: Logitech Advanced Optical Tracking, up to 4,000 DPI
• Buttons: 5
• Battery: 1 x AA, up to 24 months
• Sizes: M650, M650 L, M650 L Left
• Price: $39.99

Where it ranks

Logitech Signature M650 is No. 6 in our Best Wireless Mice verdict.