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Simple Solution Pet Urine Destroyer review

A dog-specific urine stain and odor remover that combines Pro-Bacteria and enzymes in a continuous spray bottle.

By the HearSmart research desk · Updated November 11, 2026

Performance (40%)
8.2
Ease of use (25%)
8.0
Value (35%)
7.8

Simple Solution's Pet Urine Destroyer pairs enzymes with what the company calls 2X Pro-Bacteria, a dog-specific formula meant to break down, neutralize and permanently remove urine stains and odor and discourage future marking of the same spot. The maker says it is safe on carpet, upholstery, bedding, fabric toys and other water-safe surfaces when used as directed, and it is certified by the Carpet and Rug Institute. Directions are to saturate the area, let it sit 10 minutes, blot, and let it dry naturally, which Simple Solution says may take 24 to 48 hours; it guarantees the stain and odor are gone once dry. That long drying time is the main drawback on a mattress you need to sleep on. The brand does not sell direct, so the US price is pending. We compared documented features and published prices and did not test it.

Who it is for

Dog owners who want a cleaner that says it is safe on bedding and also discourages re-marking.

Price

See vendor pricing (USD check pending).

US price check pending. See the vendor pricing page.

Key features

  • 2X Pro-Bacteria and enzyme formula for dog urine
  • Safe on carpet, upholstery, bedding and other water-safe surfaces, per the maker
  • Certified by the Carpet and Rug Institute
  • Continuous Power Spray for deep penetration
  • Stain and odor removal guaranteed once dry

Strengths and weaknesses

  • Strength: Bedding is named on the vendor's surface list
  • Strength: Guarantee that the stain and odor disappear when dry
  • Strength: Formula aims to stop pets marking the same spot
  • Weakness: Drying takes 24 to 48 hours, a long time for a bed
  • Weakness: No direct store, so price depends on the retailer
  • Weakness: Small 17 oz bottle

Key facts

  • Size: 17 oz
  • Formula: Pro-Bacteria and enzymes
  • Certification: CRI certified
  • Drying time: 24 to 48 hours

Where it ranks

Simple Solution Pet Urine Destroyer is No. 7 in our Best Mattress Stain and Urine Cleaners verdict.

Alternatives we scored

Visit simplesolution.com · Questions or corrections: editorial@hearsmart.org